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Pharmaceutical

Regeneron Pharmaceuticals, Tarrytown, NY

Project:

Regeneron Pharmaceuticals, Tarrytown, NY

Type:

Scale Up Complex

Services:

Programming, Lab Planning, Design

Owner:

BioMED

Size:

250,000 SF, 35 Acres

Budget:

Confidential

 

Background

This developer-driven research complex is composed of three, 3-storey, 125,000 SF buildings. The facility’s research focus was on diseases of the eye, therapeutics, inflammatory conditions and gout. The team was retained for all fit-out components, including a 32,500 SF barrier vivarium facility for a variety of animal models, sterile surgery, profusion and 12 procedural rooms, and cage / rack was area. The program also included over 100,000 NSF of lab spaces consisting of analytical and assay development labs; high through-put screening labs; 18,000 SF cGMP 20/50 L to 100/500 L pilot scale-up manufacturing; and FDA compliant process areas for clinical trials. The new facility also included marketing, sales, compliance, administrative and executive suites areas. Landscape was designed to support a variety of corporate and recreational functions, with the courtyard areas scaled for sports activities and detailed to accommodate overflow parking while maintaining a tranquil atmosphere.

Challenges

•

To coordinate with the core and shell team the necessary fundamental changes to the building to allow for specialize research programs

•

Responding to clients program changes which increased occupancy by 150 FTE

•

IBudget constraints with a changing program

•

Design of a non-cGMP scale-up area which could be validated as cGMP

•

Design of an office hotel concept

Solutions

•

Programming a 76% efficiency in utilization of the floor areas

•

A circulation design that allowed for the movement of research models through the lab areas

•

Increasing research vivarium population and providing multiple surgery and procedural areas

•

Design of a cost effective scale-up area for manufacturing prototyping

•

Design of an office hotel concept for increase in FTE occupancy


Services provided on behalf of KingStubbins



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